Leadership

IBD Plexus Leadership Team

The following group ensures that our data ecosystem remains aligned with its mission. Tasked with overseeing daily activities, the team also leads the development and implementation of all policies and guidelines.

Leadership Team | Scientific Advisors

Alan Moss, MD

Alan Moss, MD

Chief Scientific Officer

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Dr. Alan Moss earned his medical degree from RCSI School of Medicine in Ireland and completed his internal medicine and gastroenterology training in Dublin and Beth Israel Deaconess Medical Center of Boston (BIDMC). His prior leadership roles include Director of Translational Research at BIDMC, Director of the Crohn's & Colitis Program, and Interim Chief of Gastroenterology, at Boston Medical Center (BMC). His academic roles included Associate Professor of Medicine at Harvard Medical School and Professor of Medicine at BU School of Medicine.

 

Before joining the Foundation as Chief Scientific Officer, Dr. Moss worked with the Foundation in various roles - from being an active member of the Professional Education Committee and the New England Chapter Advocacy Committee to contributing his expertise to Grant Review Panels. Dr. Moss has extensive experience collaborating with industry, from biotechnology start-ups to sponsors of phase II and III clinical trials. He has also led Principal Investigator-initiated trials, held investigational new drug applications from the FDA, and spoken globally at IBD meetings as a key opinion leader. He has published over 200 peer-reviewed papers in academic journals, and his research has been funded by the National Institute of Diabetes and Digestive and Kidney Diseases, the American Gastroenterological Association, and the Helmsley Charitable Trust.

 

Dr. Moss brings his perspective from clinical and academic practice to support the Foundation's strong legacy in IBD education, support, research, and advocacy. He has worked with many underserved groups with IBD, including unhoused and incarcerated patient populations. His passion for patient empowerment, and appreciation of the diverse mix of patients with IBD, informs his strategy for driving the Foundation’s mission forward.

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Angela Dobes, MPH

Angela Dobes, MPH

Senior Vice President, IBD Plexus

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Angela Dobes, MPH, Senior Vice President, IBD Plexus, is responsible for the overall success and growth of the IBD Plexus program, including delivering against its core goal of accelerating R&D timelines and advancing precision medicine strategies.

 

Angela devotes much of her time to advancing high-impact, patient-centered research and is passionate about ensuring research, care interventions and treatments are meaningful to patients. Her work has been funded through organizations such as the Patient-Centered Outcomes Research Institute and The Leona M. and Harry B. Helmsley Charitable Trust. She also strives to elevate the important role patient registries and biorepositories play in the pursuit of high-value research through her roles on external committees and initiatives, including The National Academies of Science, Engineering & Medicine project titled, Data Capacity for Patient-Centered Outcomes Research: An Agenda for 2021 to 2030.

 

Prior to her experience at the Foundation, Angela worked for clinical technology and pharmaceutical organizations, where she has led implementation of various technology solutions focused on business optimization and accelerating the delivery of new therapies to patients safely.

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Ben Kostiuk, PhD

Ben Kostiuk, PhD

Associate Director, Life Science Partnerships

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Ben Kostiuk, PhD, Associate Director, Life Science Partnerships, leads relationships between the IBD Plexus and industry members and ecosystem partners with the goal of increasing the usage and improving the utility of the dataset and biosamples. He has a strong background in both academia and industry. As a PhD student, he studied the role of the microbiome in infectious disease. Ben has also worked with a biotechnology company, where he helped lead efforts to use machine learning to extract biological relationships from scientific literature.

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Carol Chapman, MPH

Carol Chapman, MPH

Associate Director, Research Engagement

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Carol Chapman, MPH, Associate Director, Research Engagement, uses her background in clinical research coordination and public health to develop and implement new ways to engage patients in all research activities. She works to include diverse patient voices as experienced leaders that can help research teams provide more value to their participants. By engaging patients early and often throughout the research process, she aims to build trust, improve recruitment practices, and increase adherence to study activities.

 

Before joining the Foundation, Carol worked in the hospital, community, and digital health technology sectors where her work focused on patient recruitment, diversity in research, and building trust in groups historically harmed by medical research.

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Justine Young, MBS

Justine Young, MBS

Senior Manager, Business and Research Operations

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Justine Young, MBS, Senior Manager, Business and Research Operations, strives to maximize the value of IBD Plexus by collaborating with study teams to optimize biosample collection processes and overseeing biobank and laboratory vendors to ensure conversion of the finite biosamples into reusable high-quality data. In addition, she manages the IBD Plexus project selection process through which the IBD scientific community can gain access to and leverage IBD Plexus resources to advance patient-centered research. Prior to joining the Foundation, Justine worked in laboratory operations management for contract research organizations supporting pharmaceutical and biotechnology companies.

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Rachael Poplau

Rachael Poplau

Senior Product Manager, Digital Health and Research

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Rachael Poplau, Senior Product Manager, Digital Health and Research, is responsible for product strategy and execution. She aligns software tools and features to support the IBD Plexus platform’s vision and provide value to study networks, patients and researchers. 

Rachael has over 15 years of experience working in non-profit healthcare, including numerous projects supporting research, patient data repositories, and improving the user experience for patients, clinicians, and researchers. 

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Sirimon O’Charoen

Sirimon O’Charoen, PhD

Senior Director, Data Science

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Sirimon O’Charoen, PhD, Senior Director, Data Science, oversees the IBD Plexus data science team and leads data integration from a scientific perspective and manages the analytical team to provide data science services to researchers across academia and industry. Sirimon is highly experienced in data quality assessment, transformation, curation, wrangling, profiling, standards and ontologies in biomedical and molecular data.

Prior to joining the Foundation, Sirimon worked in life science professional services with over 10 years of experience in delivering data solutions in clinical and translational research including development of data standards, data quality assessment, data curation, data management process, and system biology.

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Tara Fehlmann

Tara Fehlmann, MHS

Manager, Data Science and Analytics

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Tara Fehlmann, Manager, Data Science and Analytics, facilitates patient-centered research by helping investigators navigate the multi-modal data available through IBD Plexus. To jump start data analysis, Tara creates data products that help clean, wrangle, and synthesize the data into a collection of ready for research data tables. Along with curating data for research, she is instrumental in essential data monitoring and reporting which ensures the data accurately reflects a patient’s disease and treatment journey.

 

Tara has a background in epidemiology and data management, with strong academic research experience in genetic epidemiology.

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Scientific Advisors

James Lewis, MD, MSCE

James Lewis, MD, MSCE

Chief Scientist

Professor of Medicine and Epidemiology | University of Pennsylvania

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James Lewis, MD, MSCE, is Professor of Medicine and Epidemiology in the Division of Gastroenterology and Hepatology at the University of Pennsylvania’s Perelman School of Medicine. He is also a Senior Scholar in the Center for Clinical Epidemiology and Biostatistics, Chief of Gastroenterology at Penn Presbyterian Medical Center, Associate Director of the University of Pennsylvania’s Inflammatory Bowel Disease Program, and Director of the NIH-funded T32 Training Grant in GI Epidemiology. He serves as the director of the Human Research Core of Penn’s Center for Nutrition Science and Medicine and co-director of the P30-funded Biomedical Data Science Core in the Center for Molecular Studies of Gastrointestinal and Liver Disease. 

 

For more than 25 years, Dr. Lewis has been actively involved in clinical research related to inflammatory bowel diseases and other gastrointestinal diseases with goal of improving patients’ outcomes by optimizing the use of medical therapies, diagnostic tests, and nutrition. His work has been funded by the NIH, AHRQ, PCORI, CDC and numerous foundations and corporate sponsors. He is currently the lead scientist for the Crohn’s & Colitis Foundation’s IBD Plexus Research Program.

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Brigid S. Boland, MD

Brigid S. Boland, MD

Associate Chief Scientist, Translational Research

Associate Professor of Medicine | University of California, San Diego

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Brigid S. Boland, MD, is an Associate Professor of Medicine in the Division of Gastroenterology and Hepatology at the University of California, San Diego. She is the Director of Translational Inflammatory Bowel Disease Research at UCSD. She is the Director of the UCSD IBD Biorepository and is the co-Director of the P30-funded Translational Core for the San Diego Digestive Diseases Research Center.

 

She is actively involved in translational research aiming to better underlying the pathophysiology of inflammatory bowel diseases and develop biomarkers to predict response to therapy. She is the Principal Investigator on multiple industry-sponsored clinical trials. She has been funded by a CCF Career Development Award and NIH K23. She is the principal investigator on multiple industry grants. She is funded by a CCF award and Helmsley Charitable Trust grant.

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Curtis Huttenhower, PhD

Curtis Huttenhower, PhD

Associate Chief Scientist, Translational Bioinformatics

Professor of Computational Biology and Bioinformatics | Harvard T.H. Chan School of Public Health

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Dr. Curtis Huttenhower is a Professor of Computational Biology and Bioinformatics in the Departments of Biostatistics and Immunology and Infectious Diseases at the Harvard T.H. Chan School of Public Health, where he co-directs the Harvard Chan Microbiome in Public Health Center. He is an Associate Member at the Broad Institute's Microbiome Program. His lab focuses on computational methods for functional analysis of microbial communities and molecular epidemiology of the human microbiome. This includes systems biology reconstructions integrating metagenomic, metatranscriptomic, and other microbial community 'omics; the microbiome in diseases such as IBD; and its potential as a diagnostic tool and point of therapeutic intervention.

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Sean Mooney, PhD

Sean Mooney, PhD

Associate Chief Scientist, Biomedical Informatics

Professor of Biomedical Informatics and Medical Education | University of Washington

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Sean Mooney is the Chief Research Information Officer (CRIO) of UW Medicine, the Interim Director of the UW Institute for Medical Data Science, the Director of Informatics for the Institute of Translational Health Sciences, an Associate Director of the National Alzheimer's Coordinating Center (NACC), and a Professor in the Department of Biomedical Informatics and Medical Education at the University of Washington.

 

As CRIO, he leads the growing Research Information Technology team that contributes to a number of national research networks the National Kidney Precision Medicine Project, the National Alzheimer’s Coordinating Center, the UW Clear Center, and others. Some notable efforts include leading the team that developed the open-source Leaf application for clinical data querying and extraction, managed a REDCap instance with >25k projects and >10k active users, managing the Fred Hutch Cancer Center and UW joint Clinical Trials Management System application, and enhancing the UW Medicine EDW with advanced analytics including NLP. Currently, he is focusing on developing an Epic EHR Research team for supporting research in the EHR at UW Medicine and leading the newly founded UW Institute for Medical Data Science.

 

His research interests focus on data science applications in biomedicine, particularly in understanding the underlying molecular causes of inherited genetic diseases and cancer. Over his career, he has been on the faculty at Indiana University, the University of Washington, and the Buck Institute and has taught at Stanford University, UCSF, and the University of California Berkeley.  He is an expert in a wide range of STEM fields, having been trained in chemistry and computer science, and appointed at different times in his career as a faculty member in many areas including genetics, microbial biology, informatics, and gerontology. A prolific speaker, he has given more than 150 invited seminars throughout the world.

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