Modified: March 25, 2022

Dear @[email protected],

Your healthcare team has discussed the following subject with you: sulfasalazine. The brand name is Azulfidine. Here is some additional information. Let us know if you have any questions regarding this information.

  • This medication belongs to a class of drugs called aminosalicylates, which are also known as 5-ASAs. It helps to reduce the irritation and swelling (inflammation) in the lining of the intestines.

  • If taken as prescribed, these medications can work as quickly as 2 to 4 weeks.

  • The benefit of taking this medication is that it is generally well tolerated and has not been associated with an increased risk for infection or cancer. However, in some cases, it may cause headache, nausea, abdominal pain and cramping, loss of appetite, vomiting, rash, fever, or diarrhea. It is rare that this medication causes injury to your pancreas or kidneys. However, those with kidney problems should not use this medication. Your healthcare team will be monitoring your kidney function annually.

  • If you have unpleasant side effects or you continue to have symptoms, speak to your healthcare team immediately.

  • Before taking this medication, let your healthcare team know about other medical conditions that you may have or other medications (even over-the-counter medications or alternative therapies) you may be taking.

  • Taken as a pill.

  • If you have a sulfa allergy, you should not take this medication.

  • This medication should be given in combination with folic acid daily.

  • For men, this medication can cause a decrease in sperm production and function. However, sperm count becomes normal once you stop taking the medication.

  • If you are planning to have a child, speak with your healthcare team before taking this medication.

  • The best way to control your disease is by taking your medication as directed. Even when you do not have any symptoms, it is very important to continue taking your medication to prevent your disease from becoming active again. Do not alter the amount of the medication or how frequently you take it on your own.

For further information, please check out or follow this link:

PDF /sites/default/files/2020-03/aminosalicylates.pdf