Recognizing the importance of environmental factors in IBD

Recognizing the importance of environmental factors in IBD

Environmental Triggers Initiative

The importance of genetic susceptibility in inflammatory bowel diseases (IBD) has been established in the last decade and risk genes have been identified. However, the lack of complete gene penetrance and the rapid rise of IBD incidence in certain geographic regions suggest that the interaction between genetic and environmental factors contribute to IBD. Several environmental risk factors including drugs (antibiotics), viruses, psychological stress, air pollutants, diet, and chemicals, have been explored but the data is still inconclusive.

Recognizing the importance of environmental factors in IBD, the Crohn's & Colitis Foundation launched the Environmental Triggers Initiative and identified two initial focus areas: 1) viruses, and 2) psychological stress. The Foundation is announcing two Requests for Proposals (RFPs) to explore the possible role of these environmental factors in IBD susceptibility, exacerbation, progression and relapse.

Funding will be up to $900,000 per project, over a three year period ($300,000/year), contingent on reaching agreed-upon pre-established milestones. Local and international researchers are encouraged to apply.

For eligibility, policies, and application instructions:

Applicants interested in applying for the awards should submit a full proposal by October 2nd, 2017.

How to apply

Applications are not currently being accepted for this RFP.

Questions? Contact Nataly Shtraizent at