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Featured Study Opportunities

The Crohn's & Colitis Foundation utilizes Featured Study Opportunities to collaborate with academic and industry researchers to help enroll patients with Crohn’s disease and ulcerative colitis into clinical studies. The list below highlights our partners' current research studies. Please note that these partners have paid to have their trials posted below. Some partners' studies listed may be recipients of partial or full funding from the Crohn's & Colitis Foundation. This support does not imply recommendation or favor of the Foundation, as the Crohn's & Colitis Foundation does not endorse any particular study.

 

For a comprehensive listing of all research studies currently recruiting, please click here.

To search by state use state code:
(For e.g NY instead of New York)
To search by state use state code:
(For e.g NY instead of New York)
Clinical Trials Phases
  • (X) Phase 2 (37)

Current Results: 37 entries

A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥ 18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED) (Study in Ulcerative...)
Phase 2
Sponsor: Sanofi - LIBERTY UC
Description:

The main purpose of this study is to evaluate the effect of dupilumab on relieving symptoms of ulcerative colitis and reducing inflammation in the colon.

Recruiting Now »
A Study to Test the Effect of TEV-48574 in Moderate to Severe Ulcerative Colitis or Crohn's Disease (RELIEVE UCCD)
Phase 2
Sponsor: Teva Branded Pharmaceutical Products R&D, Inc
Description:

The primary objective of the study is to evaluate the efficacy and dose response of 3 different dose regimens of TEV‑48574 subcutaneous (sc) administered every 2 weeks (Q2W) in adult patients with IBD (moderate to severe UC or CD) as assessed by induction of clinical remission (UC) and endoscopic response (CD) at week 14.

Recruiting Now »
An Open-Label, Single-Arm Study to Evaluate the Efficacy, Pharmacokinetics, and Safety of Etrasimod in Adolescent Participants with Moderately to Severely Active Ulcerative Colitis
Phase 2
Sponsor: Arena Pharmaceuticals Inc.
Description:

The purpose of this study is to determine whether oral etrasimod is a safe and effective treatment for moderately to severely active ulcerative colitis in adolescents (≥ 12 years up to < 18 years of age).

Recruiting Now »
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis
Phase 2
Sponsor: Bristol Myers Squibb Peds UC
Description:

To evaluate the efficacy and safety of ozanimod in pediatric participants with moderately to severely active UC.

Recruiting Now »
A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Crohn’s Disease
Phase 2
Sponsor: Bristol Myers Squibb Peds CD
Description:

To evaluate the efficacy of ozanimod in pediatric participants with moderately to severely active Crohn's disease.

Recruiting Now »
A Phase 2, Dose-finding, Randomized, Double-blind, Placebo-controlled, Multicenter Study to Evaluate the Safety and Efficacy of Efavaleukin Alfa Induction Therapy in Patients with Moderately to Severely Active Ulcerative Colitis
Phase 2
Sponsor: Amgen
Description:

To evaluate the effect of efavaleukin alfa on induction of clinical remission.

Recruiting Now »
A Phase 2a, Randomized, Double-blinded, Placebo-controlled Study to evaluate Safety and Efficacy of Fecal Microbiota Transplantation Capsules administered with Standard-of-Care therapy for Prevention of Relapse in Adults with Ulcerative Colitis
Phase 2
Sponsor: University of Texas Health Science Center at Houston (UTHealth)
Description:
  • To prevent relapse in patients with Ulcerative Colitis (UC) in remission after administering fecal microbiota transplant (FMT) capsules plus Standard-Of-Care (SOC) treatment compared to placebo plus SOC treatment for 12 weeks.
  • To evaluate the safety of FMT capsules given orally for 12 weeks in patients with UC in remission.
Recruiting Now »
Natural Product Signature in Adults with Crohn’s Disease
Phase 2
Sponsor: National University of Natural Medicine - Helfgott Research Institute
Description:

To assess the safety of, as well as how a natural product derived from the Hops plant is broken down by the bacteria in the intestines of adults with Crohn’s disease. 

Recruiting Now »
To Evaluate the Safety and Efficacy of PN-943 Treatment in Patients with Moderate to Severe Active Ulcerative Colitis.
Phase 2
Sponsor: Protagonist Therapeutics, Inc.
Description:

To Evaluate the Safety and Efficacy of PN-943 Treatment in Patients with Moderate to Severe Active Ulcerative Colitis.

Recruiting Now »
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2a Study to Evaluate the Safety, Tolerability, and Early Proof of Concept of TAK-018 for the Prevention of Postoperative Crohn’s Disease Recurrence
Phase 2
Sponsor: Takeda TAK-018 Study
Description:

To assess the safety and tolerability and early proof of efficacy of TAK-018 in patients with Crohn’s Disease who are planning to undergo surgery to remove the diseased ileo-cecal region of the bowel.

Recruiting Now »

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If you are interested in listing your trial on the Featured Study Opportunities page, please contact [email protected]

The Featured Study Opportunities page is made possible in part by:

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