Azulfidine® ,
Sulfasalazine
Disease
Ulcerative colitis
,
Drug Class
Aminosalicylates (5-ASA)
Delivery Method

Oral
or
Brand name:
Azulfidine®
,
Drug name:
Sulfasalazine
Recommendations for pregnancy
Considered low risk; give folate 2 mg daily
Recommendations for breastfeeding
Limited human data: potential diarrhea. Females and males of reproductive potential: Sulfasalazine decreases sperm count and therefore may cause infertility.
Most common side effects
Diarrhea, headache, loss of appetite, upset stomach, vomiting, and stomach pain
Other
Low sperm count and infertility have been observed in men treated with sulfasalazine; however, withdrawal of the drug appears to reverse these effects
Learn more about
Aminosalicylates (5-ASA)