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Featured Study Opportunities

The Crohn's & Colitis Foundation utilizes Featured Study Opportunities to collaborate with academic and industry researchers to help enroll patients with Crohn’s disease and ulcerative colitis into clinical studies. The list below highlights our partners' current research studies. Please note that these partners have paid to have their trials posted below. Some partners' studies listed may be recipients of partial or full funding from the Crohn's & Colitis Foundation. This support does not imply recommendation or favor of the Foundation, as the Crohn's & Colitis Foundation does not endorse any particular study.

 

For a comprehensive listing of all research studies currently recruiting, please click here.

To search by state use state code:
(For e.g NY instead of New York)
To search by state use state code:
(For e.g NY instead of New York)
Clinical Trials Phases
  • (X) Phase 1 (8)

Current Results: 8 entries

ExoFlo for Crohn's disease: A Phase I study of ExoFlo, an ex vivo culture-expanded adult allogeneic bone marrow mesenchymal stem cell derived extracellular vesicle isolate product, for the treatment of medically refractory Crohn's disease
Phase 1
Sponsor: Direct Biologics CD Study
Description:

To evaluate the usefulness, safety, and effectiveness of intravenous ExoFlo in patients with Crohn’s disease who are not responding to conventional therapies.

 

Recruiting Now »
ExoFlo for ulcerative colitis: A Phase I study of ExoFlo, an ex vivo culture-expanded adult allogeneic bone marrow mesenchymal stem cell derived extracellular vesicle isolate product, for the treatment of medically refractory ulcerative colitis
Phase 1
Sponsor: Direct Biologics UC Study
Description:

To evaluate the usefulness, safety, and effectiveness of intravenous ExoFlo in patients with ulcerative colitis who are not responding to conventional therapies.

Recruiting Now »
A Phase IB/IIA Study of ExoFlo, an Ex Vivo Culture-expanded Adult Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product, for the Treatment of Perianal Fistulizing Crohn’s Disease
Phase 1
Sponsor: Direct Biologics PFCD Study
Description:

To evaluate the safety and effectiveness of ExoFlo in patients with perianal fistula(s) due to Crohn’s disease.

Recruiting Now »
Study to Evaluate Safety, Tolerability, and Early Efficacy of Oral E-B-FAHF-2 in Subjects with Mild-to-Moderate Crohn’s Disease
Phase 1
Sponsor: Mount Sinai Hospital - Susan and Leonard Feinstein Inflammatory Bowel Disease Clinical Center
Description:

Primary Objective: Safety and Tolerability

Secondary Objective: Efficacy

Recruiting Now »
Study of Dietary Composition in Crohn's Disease
Phase 1
Description:

Understand how diet influences inflammation, symptoms, and the biology of Crohn's disease

Recruiting Now »
A Phase 1 Study of Drug Interactions with a Study Drug for Inflammatory Conditions
Phase 1
Sponsor: Pfizer New Haven
Description:

This is a clinical trial with healthy participants to:
• see how the study drug is tolerated, if there are significant side effects, and how people feel after taking it when given with a single dose of another medication (drug B)
• see if multiple doses of the study drug have an effect on the amount of drug B in your blood after a single dose 
• measure how much of drug B is in your blood after you take a single dose  

Recruiting Now »
A Phase 1 Investigation of a Study Drug for Inflammatory Conditions in Healthy Adult Participants
Phase 1
Sponsor: Pfizer New Haven 2
Description:

This is a clinical trial with healthy participants to:
• measure how a single oral dose of the study drug affects the body and certain types of blood cells and enzymes
• measure the amount of study drug in your blood 48 hours after a single dose 
• see how a new drug under study is tolerated, if there are any significant side effects and how people feel after taking it

Recruiting Now »
A Phase 1/2a Double-Blind, Randomized, Placebo-Controlled Trial to Assess the Safety and Efficacy of Oral Administration of EcoActive on Intestinal Adherent Invasive Escherichia coli (AIEC) in Patients With Inactive Crohn’s Disease (CD)
Phase 1
Sponsor: Intralytix
Description:

The study objectives are to: 1) assess the safety of oral administration of EcoActive (twice daily, for 15 days) in patients with clinically inactive Crohn’s disease having Adherent Invasive Escherichia coli (AIEC) present in their stools; and, 2) evaluate changes in AIEC incidence and levels in stools of patients receiving treatment versus placebo-treated controls.

Recruiting Now »
If you are interested in listing your trial on the Featured Study Opportunities page, please contact [email protected]

The Featured Study Opportunities page is made possible in part by:

PPD

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