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Featured Study Opportunities

The Crohn's & Colitis Foundation utilizes Featured Study Opportunities to collaborate with academic and industry researchers to help enroll patients with Crohn’s disease and ulcerative colitis into clinical studies. The list below highlights our partners' current research studies. Please note that these partners have paid to have their trials posted below. Some partners' studies listed may be recipients of partial or full funding from the Crohn's & Colitis Foundation. This support does not imply recommendation or favor of the Foundation, as the Crohn's & Colitis Foundation does not endorse any particular study.

 

For a comprehensive listing of all research studies currently recruiting, please click here.

To search by state use state code:
(For e.g NY instead of New York)
To search by state use state code:
(For e.g NY instead of New York)
Clinical Trials Phases
  • Phase 2 (31)
  • Other (18)
  • Phase 3 (15)
  • Phase 1 (8)
  • Observational Study (5)
  • open label extension (4)
  • Survey (2)

Current Results: 84 entries

ExoFlo for Crohn's disease: A Phase I study of ExoFlo, an ex vivo culture-expanded adult allogeneic bone marrow mesenchymal stem cell derived extracellular vesicle isolate product, for the treatment of medically refractory Crohn's disease
Phase 1
Sponsor: Direct Biologics CD Study
Description:

To evaluate the usefulness, safety, and effectiveness of intravenous ExoFlo in patients with Crohn’s disease who are not responding to conventional therapies.

 

Recruiting Now »
ExoFlo for ulcerative colitis: A Phase I study of ExoFlo, an ex vivo culture-expanded adult allogeneic bone marrow mesenchymal stem cell derived extracellular vesicle isolate product, for the treatment of medically refractory ulcerative colitis
Phase 1
Sponsor: Direct Biologics UC Study
Description:

To evaluate the usefulness, safety, and effectiveness of intravenous ExoFlo in patients with ulcerative colitis who are not responding to conventional therapies.

Recruiting Now »
A Phase IB/IIA Study of ExoFlo, an Ex Vivo Culture-expanded Adult Allogeneic Bone Marrow Mesenchymal Stem Cell Derived Extracellular Vesicle Isolate Product, for the Treatment of Perianal Fistulizing Crohn’s Disease
Phase 1
Sponsor: Direct Biologics PFCD Study
Description:

To evaluate the safety and effectiveness of ExoFlo in patients with perianal fistula(s) due to Crohn’s disease.

Recruiting Now »
FUZION: Efficacy and Safety of an investigational medication in participants with Fistulizing, Perianal Crohn’s Disease
Phase 3
Sponsor: Janssen FUZION Study
Description:

The purpose of the FUZION Study is to evaluate the efficacy and safety of the investigational study medication in participants with Fistulizing, Perianal Crohn’s Disease

Recruiting Now »
A Phase 2b Multicenter, Randomized, Placebo-Controlled, Dose-Ranging Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Moderately to Severely Active Ulcerative Colitis
Phase 2
Sponsor: Janssen Anthem-UC Study
Description:

Primary objective is to evaluate the efficacy of JNJ-77242113 versus placebo in inducing clinical response.

Recruiting Now »
DUET-UC: A study of an investigational study medication in participants with Moderately to Severely Active Ulcerative Colitis
Phase 2
Sponsor: DUET - UC Study
Description:

The purpose of the DUET study is to evaluate the efficacy and safety of the investigational combination therapy with two investigational study medications in participants with moderately to severely active Ulcerative Colitis.

Recruiting Now »
DUET-CD: A study of an investigational study medication in participants with Moderately to Severely Active Crohn's Disease
Phase 2
Sponsor: DUET - CD Study
Description:

The purpose of the DUET study is to evaluate the efficacy and safety of the investigational combination therapy of two investigational medications in participants with moderately to severely active Crohn's disease.

Recruiting Now »
ABTECT Program (ABX464 Treatment Evaluation for ulcerative Colitis Therapy) (ABX464-107)
Phase 3
Sponsor: Abivax SA
Description:

Patients who completed the induction treatment of 8 weeks can roll over into a subsequent maintenance study with the objective to evaluate long-term safety and efficacy of obefazimod (ABX464). The maintenance trial consists of a 44-weeks treatment period followed by a 4-weeks follow-up period.

 

Recruiting Now »
A randomized, double-blind, placebo controlled, dose finding study to assess the efficacy and safety of SAR443122 in adult patients with moderate to severe ulcerative colitis (RESOLUTE)
Phase 2
Sponsor: Sanofi - RESOLUTE
Description:

The goal of this study is to see how well the study medicine works to treat ulcerative colitis (UC), as well as to see if the study medicine has any side effects. This study will test different doses of the study medicine in participants with moderate to severe UC to find the dose with the best results.

Recruiting Now »
A Study to Investigate the Efficacy and Safety of Dupilumab Therapy Compared With Placebo in Participants Aged ≥ 18 Years With Moderately to Severely Active Ulcerative Colitis With an Eosinophilic Phenotype (LIBERTY-UC SUCCEED) (Study in Ulcerative...)
Phase 2
Sponsor: Sanofi - LIBERTY UC
Description:

The main purpose of this study is to evaluate the effect of dupilumab on relieving symptoms of ulcerative colitis and reducing inflammation in the colon.

Recruiting Now »

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If you are interested in listing your trial on the Featured Study Opportunities page, please contact [email protected]

The Featured Study Opportunities page is made possible in part by:

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