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Featured Study Opportunities

The Crohn's & Colitis Foundation utilizes Featured Study Opportunities to collaborate with academic and industry researchers to help enroll patients with Crohn’s disease and ulcerative colitis into clinical studies. The list below highlights our partners' current research studies. Please note that these partners have paid to have their trials posted below. Some partners' studies listed may be recipients of partial or full funding from the Crohn's & Colitis Foundation. This support does not imply recommendation or favor of the Foundation, as the Crohn's & Colitis Foundation does not endorse any particular study.

 

For a comprehensive listing of all research studies currently recruiting, please click here.

To search by state use state code:
(For e.g NY instead of New York)
To search by state use state code:
(For e.g NY instead of New York)
Clinical Trials Phases
  • Phase 2 (31)
  • Other (18)
  • Phase 3 (15)
  • Phase 1 (8)
  • Observational Study (5)
  • open label extension (4)
  • Survey (2)

Current Results: 84 entries

Investigating the role of human exposome in Crohn’s disease
Other
Sponsor: Stanford University
Description:

This Stanford University study aims to identify potential environmental exposure markers that may contribute to the progression of Crohn's disease. 

Recruiting Now »
To Evaluate the Safety and Efficacy of PN-943 Treatment in Patients with Moderate to Severe Active Ulcerative Colitis.
Phase 2
Sponsor: Protagonist Therapeutics, Inc.
Description:

To Evaluate the Safety and Efficacy of PN-943 Treatment in Patients with Moderate to Severe Active Ulcerative Colitis.

Recruiting Now »
A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase 2a Study to Evaluate the Safety, Tolerability, and Early Proof of Concept of TAK-018 for the Prevention of Postoperative Crohn’s Disease Recurrence
Phase 2
Sponsor: Takeda TAK-018 Study
Description:

To assess the safety and tolerability and early proof of efficacy of TAK-018 in patients with Crohn’s Disease who are planning to undergo surgery to remove the diseased ileo-cecal region of the bowel.

Recruiting Now »
A Multicenter, Randomized, Double-Blind, Parallel-Group Study to Assess the Efficacy and Safety of Oral Etrasimod as Induction and Maintenance Therapy for Moderately to Severely Active Crohn’s Disease
Phase 2
Sponsor: Arena Pharmaceuticals, Inc.
Description:

To evaluate the dose-response relationship of two doses of etrasimod versus placebo as induction therapy in participants with moderately to severely active Crohn’s disease.

Recruiting Now »
A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study of the Safety, Efficacy, and Biomarker Response of BMS-986165 in Patients with Moderate to Severe Ulcerative Colitis
Phase 2
Sponsor: Bristol-Myers Squibb
Description:

The purpose of the study is to evaluate the safety and effectiveness of the study medicine in adults with ulcerative colitis.

Recruiting Now »
Multicenter, randomized, double-blind, placebo-controlled phase II clinical trial to evaluate the effectiveness and safety of CBP-307 in subjects with moderate to severe ulcerative colitis (UC)
Phase 2
Sponsor: Suzhou Connect Biopharmaceuticals, Ltd.
Description:

Primary objective: To compare clinical efficacy by evaluating the clinical response to CBP-307 (P.O. for 12 consecutive weeks) versus placebo in subjects with moderate to severe UC

Recruiting Now »
Lattice Study for Crohn’s Disease (LATTICE-CD): A Phase 2 Randomized, Double-Blind, Placebo- Controlled Study of the Safety and Efficacy of BMS 986165 in Participants with Moderate to Severe Crohn's Disease
Phase 2
Sponsor: Bristol-Myers Squibb
Description:

The purpose of the LATTICE-CD is to evaluate how well an oral investigational drug (called BMS- 986165) works and how safe it is for patients with moderately to severely active Crohn’s disease.

Recruiting Now »
Qualitative Research to Explore Bowel Urgency and Disease Remission in Adults with Ulcerative Colitis
Other
Sponsor: Eli Lilly and Company
Description:
  • We are conducting interviews with adults who have been clinically diagnosed with Ulcerative Colitis (UC) that is currently moderately-to-severely active based on clinician assessment.
  • The focus of the interviews will be to gain a better understanding of the participant's experience living with ulcerative colitis, including what symptoms are most important to them and how these symptoms may impact their day-to-day life.
Recruiting Now »
Safety and Feasibility of Oligofructose-Enriched Inulin in Pediatric Inflammatory Bowel Disease. Short title: The TII Trial: Treating IBD with Inulin (TII)
Phase 3
Sponsor: Children's Hospital of Philadelphia and Crohn's and Colitis Foundation
Description:
  • To evaluate the effect of the prebiotic fiber inulin on the microbiome of children with IBD who have subclinical disease activity (patients with no symptoms but elevated fecal calprotectin)
  • To evaluate the efficacy of the prebiotic fiber inulin in reducing gut inflammation (fecal calprotectin) in IBD

 

Recruiting Now »
A Phase 1/2a Double-Blind, Randomized, Placebo-Controlled Trial to Assess the Safety and Efficacy of Oral Administration of EcoActive on Intestinal Adherent Invasive Escherichia coli (AIEC) in Patients With Inactive Crohn’s Disease (CD)
Phase 1
Sponsor: Intralytix
Description:

The study objectives are to: 1) assess the safety of oral administration of EcoActive (twice daily, for 15 days) in patients with clinically inactive Crohn’s disease having Adherent Invasive Escherichia coli (AIEC) present in their stools; and, 2) evaluate changes in AIEC incidence and levels in stools of patients receiving treatment versus placebo-treated controls.

Recruiting Now »

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If you are interested in listing your trial on the Featured Study Opportunities page, please contact [email protected]

The Featured Study Opportunities page is made possible in part by:

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