Xeljanz® ,
Tofacitinib
Disease
Ulcerative colitis
,
Drug Class
Targeted Synthetic Small Molecules
Delivery Method
Oral
Brand name:
Xeljanz®
,
Drug name:
Tofacitinib
Drug type
JAK Inhibitor
Recommendations for pregnancy
Risks associated to mother and fetus in pregnancy. Pregnancy planning should be considered in women of reproductive age.
Recommendations for breastfeeding
No information on presence of this medication within human breast milk. Tofacitinib was found present in milk of lactating animal models. Breastfeeding while taking this medication is not advised.
Most common side effects
Common side effects may include infections in nose or sinus, headache, nausea, diarrhea, rash, throat irritation, high cholesterol, gastroenteritis, anemia, upper respiratory infection. Risks of lymphoma and other cancers are rare.
Other
Patients should be tested for tuberculosis prior to starting tofacitinib. Avoid taking live vaccines while taking tofacitinib.
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Targeted Synthetic Small Molecules